× Important note: Due to the end of funding, these reviews are no longer in living mode. We try to update them on a monthly basis.

meta|Evidence - COVID-19

Living meta-analysis and evidence synthesis of therapies for COVID19  

Member of the meta|Evidence galaxy

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Treament Trials
Statistically conclusive or suggested result Inconclusive results Uncertain results Safety results
0- - - -
0- - - -
2 noneinconclusive results for: death D28; deep vein thrombosis; elevated liver enzymes; hyperbilirubinemia; pulmonary embolism; renal impairment

suggested 45 % decrease in deaths but the degree if certainty is unassessable

suggested 45 % decrease in deaths (time to event analysis only) but the degree if certainty is unassessable

suggested 29 % increase in clinical improvement but the degree if certainty is unassessable

suggested 35 % increase in clinical improvement (28-day) but the degree if certainty is unassessable

suggested 29 % increase in clinical improvement (time to event analysis only) but the degree if certainty is unassessable

suggested 28 % decrease in serious adverse events but the degree if certainty is unassessable

-
1 noneinconclusive results for: death D28; deaths--
1 noneinconclusive results for: mechanical ventilation

statistically conclusive 13 % decrease in death D28 but the degree if certainty is unassessable

statistically conclusive 13 % decrease in deaths but the degree if certainty is unassessable

suggested 10 % decrease in death or ventilation but the degree if certainty is unassessable

-
0- - - -
0- - - -
0- - - -
0 / 1 none---
1 / 2 noneinconclusive results for: death D28; death or transfer to ICU; deaths; clinical deterioration; clinical improvement; death or ventilation; serious adverse events--
0- - - -
0- - - -
0- - - -

Statistically conclusive: statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias; suggested: nominally statistically significant but without a strict control of overall risk of type 1 error; inconclusive: not nominally statistically significant

149
treatments 		  718
studies with results 		  1743
studies screend 		  1629
references

This project is supported by a grant of the French Ministry of Health (Hospital Clinical Research Program, PHRC-N), Université de Lyon (UdL/Idex), and self-funded by Hospices Civils de Lyon, CNRS UMR5558 LBBE University Lyon-1.

     

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